类型试验信息(多次测定用,隔开)图谱读取备注
项目代号:已存用户保存
项目名称:已存用户保存
试验名称可缺:待存默认值
时间点可缺:待存默认值
图谱类型:已存HPLC用户保存
样品类型:已存自制品,参比制剂,参比制剂用户保存
批号:已存2024042711批,12235763批,12407637批用户保存
规格可缺:待存默认值
介质名称:已存pH1.2(内含0.05%SDS),pH1.2(内含0.05%SDS),pH1.2(内含0.05%SDS)用户保存
方法名称可缺:已存桨法,桨法,桨法用户保存
转速可缺:已存50转,50转,50转用户保存
组成图标坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱
自制品-2024042711批批()-pH1.2(内含0.05%SDS)-桨法-50转
注1:成分名称多个峰按出峰顺序【,】(半角逗号)隔开;
注2:试验批号和介质名称都一样的填一个;有任何不一致的需要【,】(半角逗号)隔开填写波数个;
注3:特别注意:批号和规格必须存在;
编号2219
项目名称坎地沙坦酯左氨氯地平片
选择方法
峰的筛选AUTO
根据对照品保留时间的0.95~1.05进行筛选;
对照品图谱务必只出主成分峰;
测定类型溶出
成分(个数)
成分名称
进样针数1针　2针
双波长
溶出度
图谱类型
制剂单位
姜进硙2024-08-05 15:37:32进行了保存!
返回上一页
既往测定情况概览
编号 试验名称 介质体积 取样体积 补液体积 R批号 R来源 R使用方法 R含量(%) R水分(%) R稀释 R标示量(mg) T稀释 操作
7509 900 10 10 100685-201903 中检院 直接使用 99.8 0 4000 8 2 使用
7508 900 10 10 100685-201903 中检院 直接使用 99.8 0 4000 8 2 使用
7506 900 10 10 100546-202406 中检院 直接使用 96.5 0 8000 2.5 2 使用
7504 左氨氯地平 900 10 10 100546-202406 中检院 直接使用 96.5 0 8000 2.5 2 使用
5591 稳定性12月 900 10 10 100685-201903 中检院 直接使用 99.8 0 4000 8 2 使用
5590 稳定性12月 900 10 10 100546-202105 中检院 直接使用 97.3 0 8000 2.5 2 使用
5448 900 10 10 100685-201903 中检院 直接使用 99.8 0 4000 8 2 使用
5442 使用
4778 900 10 10 100685-201903 中检院 直接使用 99.8 0 4000 8 2 使用
4777 900 10 10 100685-201903 中检院 直接使用 99.8 0 4000 8 2 使用
4776 900 10 10 100685-201903 中检院 直接使用 99.8 0 4000 8 2 使用
4775 900 10 10 100546-202105 中检院 直接使用 97.3 0 8000 2.5 2 使用
4663 900 10 10 100685-201903 中检院 直接使用 99.8 0 4000 8 2 使用
4662 900 10 10 100546-202105 中检院 直接使用 97.3 0 8000 2.5 2 使用
3795 900 10 10 100685-201903 中检院 直接使用 99.8 0 4000 8 2 使用
3794 900 10 10 100546-202105 中检院 直接使用 97.3 0 8000 2.5 2 使用
3792 使用
3680 900 10 10 100685-201903 中检院 直接使用 99.8 0 4000 8 2 使用
3678 900 10 10 100546-202105 中检院 直接使用 97.3 0 8000 2.5 2 使用
3049 900 10 10 100685-201903 中检院 直接使用 99.8 0 4000 8 2 使用
注意:::正在使用与其他方法的参数!恢复
【 坎地沙坦酯 】信息
介质体积(ml)取样体积(ml)补液体积(ml)
对照品批号对照品来源对照品使用方法
对照品含量(%)对照品水分(%)对照品稀释倍数
标示量(mg)供试品稀释倍数系数
称样量1(mg)称样量2(mg)
觜进硙2024-08-05 15:37:50进行了保存!
类型波数成分响应值RSD%
审阅状态N
审阅权限孙文新,谢鑫慧,王丹,姜进硙,邵涛明
供试品测定波数:::3次
供试品测定片数:::6片
供试品取样点数:::5min,10min,15min,20min,30min,45min,60min,极限;
对照品的峰个数:::1个峰
图谱最多峰个数:::1个峰
对照品保留时间:::3.134
对照品　峰面积:::176010
待处理PDF文件:::查阅
筛选规则为:::自动
图谱张数为:::168
2024-08-05 15:37:57姜进硙进行了保存!
序号文件名溶液名称保留时间峰面积
1zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-rj无峰无面积1NA1
2zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-13.1261753701MA1
3zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-23.1261762821MA1
4zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-33.1291760291MA1
5zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-43.1271753741MA1
6zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-53.1331756841MA1
7zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P13.125721241MA1
8zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P23.131727621MA1
9zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P33.130938531MA1
10zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P43.128821221MA1
11zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P53.129891731MA1
12zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P63.128840341MA1
13zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P13.1281314431MA1
14zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P23.1311348861MA1
15zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P33.1291341561MA1
16zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P43.1271400041MA1
17zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P53.1321430121MA1
18zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P63.1291346791MA1
19zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P13.1351522521MA1
20zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P23.1281518071MA1
21zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P33.1391572741MA1
22zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P43.1331584711MA1
23zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P53.1311578031MA1
24zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P63.1381495601MA1
25zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P13.1271536491MA1
26zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P23.1301569731MA1
27zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P33.1261582811MA1
28zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P43.1331582001MA1
29zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P53.1331634771MA1
30zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P63.1281623551MA1
31zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P13.1321643651MA1
32zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P23.1271670501MA1
33zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P33.1331720791MA1
34zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P43.1301732201MA1
35zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P53.1231676881MA1
36zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P63.1301646891MA1
37zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P13.1231681301MA1
38zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P23.1261599751MA1
39zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P33.1231699801MA1
40zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P43.1311694871MA1
41zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P53.1271657741MA1
42zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P63.1291680671MA1
43zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P13.1351614631MA1
44zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P23.1271613141MA1
45zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P33.1331627201MA1
46zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P43.1321673371MA1
47zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P53.1291663821MA1
48zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P63.1321653551MA1
49zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P13.1321580161MA1
50zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P23.1301583421MA1
51zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P33.1351652561MA1
52zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P43.1291604591MA1
53zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P53.1301601811MA1
54zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P63.1331580311MA1
55zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-dz2-13.1341765871MA1
56zzp-2024042711p-pH1.2+0.05SDSjz-jf50z-jyx2-dz2-23.1341762161MA1
57cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-rj无峰无面积1NA1
58cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-13.1361764461MA1
59cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-23.1311761011MA1
60cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-33.1331759611MA1
61cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-43.1381759101MA1
62cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-53.1311757811MA1
63cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P13.128301171MA1
64cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P23.124309201MA1
65cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P33.121309531MA1
66cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P43.131308921MA1
67cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P53.124281641MA1
68cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P63.131294681MA1
69cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P13.126676541MA1
70cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P23.132710371MA1
71cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P33.124680531MA1
72cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P43.131680221MA1
73cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P53.132682801MA1
74cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P63.123674771MA1
75cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P13.1261117681MA1
76cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P23.1321086231MA1
77cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P33.1271103131MA1
78cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P43.1241075471MA1
79cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P53.1311041931MA1
80cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P63.1301046221MA1
81cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P13.1311349241MA1
82cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P23.1301380571MA1
83cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P33.1311395981MA1
84cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P43.1321389251MA1
85cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P53.1241320031MA1
86cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P63.1301426361MA1
87cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P13.1291569351MA1
88cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P23.1271723641MA1
89cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P33.1301688631MA1
90cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P43.1311674771MA1
91cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P53.1311629881MA1
92cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P63.1331709261MA1
93cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P13.1291663801MA1
94cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P23.1391741841MA1
95cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P33.1371733441MA1
96cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P43.1381753151MA1
97cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P53.1271583231MA1
98cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P63.1331700841MA1
99cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P13.1361736061MA1
100cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P23.1311686581MA1
101cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P33.1331719601MA1
102cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P43.1311684721MA1
103cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P53.1321723301MA1
104cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P63.1311705431MA1
105cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P13.1371685411MA1
106cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P23.1261674491MA1
107cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P33.1321676691MA1
108cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P43.1391686241MA1
109cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P53.1331673941MA1
110cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P63.1301635861MA1
111cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-dz2-13.1401758221MA1
112cbzj-12235763p-pH1.2+0.05SDSjz-jf50z-jyx2-dz2-23.1341757811MA1
113cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-rj无峰无面积1NA1
114cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-13.1401765371MA1
115cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-23.1341760401MA1
116cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-33.1401762401MA1
117cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-43.1431760001MA1
118cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-dz1-53.1321757671MA1
119cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P13.124318691MA1
120cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P23.126338981MA1
121cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P33.125336211MA1
122cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P43.130284231MA1
123cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P53.127309031MA1
124cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-5min-P63.128318971MA1
125cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P13.129612971MA1
126cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P23.126710171MA1
127cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P33.130645071MA1
128cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P43.130598821MA1
129cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P53.132590811MA1
130cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-10min-P63.133689711MA1
131cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P13.130964271MA1
132cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P23.1271065821MA1
133cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P33.1311124081MA1
134cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P43.131958781MA1
135cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P53.1331057361MA1
136cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-15min-P63.1291058811MA1
137cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P13.1361242101MA1
138cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P23.1361385841MA1
139cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P33.1321401231MA1
140cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P43.1251241241MA1
141cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P53.1371361411MA1
142cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-20min-P63.1311393231MA1
143cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P13.1371586191MA1
144cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P23.1301642141MA1
145cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P33.1321689401MA1
146cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P43.1341541561MA1
147cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P53.1341654411MA1
148cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-30min-P63.1321640451MA1
149cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P13.1311767121MA1
150cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P23.1381692471MA1
151cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P33.1341790751MA1
152cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P43.1291662941MA1
153cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P53.1351729071MA1
154cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-45min-P63.1291724081MA1
155cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P13.1351757941MA1
156cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P23.1361648281MA1
157cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P33.1321726291MA1
158cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P43.1301684541MA1
159cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P53.1331706441MA1
160cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-60min-P63.1361696611MA1
161cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P13.1291604761MA1
162cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P23.1321646871MA1
163cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P33.1301697951MA1
164cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P43.1381632041MA1
165cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P53.1351615981MA1
166cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-JX-P63.1371644581MA1
167cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-dz2-13.1351763151MA1
168cbzj-12407637p-pH1.2+0.05SDSjz-jf50z-jyx2-dz2-23.1421759751MA1
计算
Current page cost:273 ms