坎地沙坦酯左氨氯地平片项目信息
介质体积(ml)
900
取样体积(ml)
10
补液体积(ml)
10
对照品批号
100685-201903
对照品来源
中检院
对照品使用方法
直接使用
对照品含量(%)
99.8
对照品水分(%)
0
对照品稀释倍数
4000
标示量(mg)
8
供试品稀释倍数
2
系数
1
对照品溶液
序号
称样量(mg)
A
1
A
2
A
3
A
4
A
5
A
平均
RSD%
1
15.95
171692
172268
171633
170909
172270
171754
0.33
2
16.07
171918
171986
171952
0.03
单位质量响应值
RSD%
判断
10768.28
10700.19
0.45
数据可信
供试品溶液-12407637批-pH6.8(内含0.1%Tween80)
时间
(分钟)
样品
A
1
A
2
A
平均
溶出量(%)
平均(%)
RSD%
累计溶
出量(%)
平均(%)
RSD%
5min
1
19099
-
19099
9.988
7.46
18.19
9.99
7.46
18.21
2
14207
-
14207
7.430
7.43
3
11366
-
11366
5.944
5.94
4
13151
-
13151
6.878
6.88
5
14259
-
14259
7.457
7.46
6
13482
-
13482
7.051
7.05
10min
1
56703
-
56703
29.655
24.06
14.41
29.77
24.14
14.42
2
49636
-
49636
25.959
26.04
3
38573
-
38573
20.173
20.24
4
46502
-
46502
24.320
24.40
5
44388
-
44388
23.214
23.30
6
40199
-
40199
21.023
21.10
15min
1
98411
-
98411
51.467
43.59
13.81
51.91
43.94
13.81
2
92529
-
92529
48.391
48.76
3
72367
-
72367
37.847
38.14
4
88370
-
88370
46.216
46.56
5
78520
-
78520
41.065
41.41
6
69857
-
69857
36.534
36.85
20min
1
136151
-
136151
71.204
61.27
13.12
72.22
62.11
13.12
2
130752
-
130752
68.381
69.29
3
104159
-
104159
54.473
55.18
4
123739
-
123739
64.713
65.57
5
110405
-
110405
57.740
58.54
6
97746
-
97746
51.119
51.84
30min
1
167856
-
167856
87.786
83.81
6.19
89.59
85.32
6.29
2
169283
-
169283
88.532
90.20
3
152561
-
152561
79.787
81.10
4
167032
-
167032
87.355
88.93
5
160203
-
160203
83.783
85.22
6
144565
-
144565
75.605
76.89
45min
1
181472
-
181472
94.907
95.01
1.91
97.69
97.46
2.02
2
182887
-
182887
95.647
98.30
3
176827
-
176827
92.477
94.68
4
185280
-
185280
96.898
99.45
5
185096
-
185096
96.802
99.17
6
178500
-
178500
93.352
95.48
60min
1
184981
-
184981
96.742
96.31
1.75
100.58
99.82
1.84
2
182643
-
182643
95.519
99.23
3
179420
-
179420
93.833
97.06
4
188581
-
188581
98.624
102.25
5
186434
-
186434
97.502
100.95
6
182905
-
182905
95.656
98.82
极限
1
174212
-
174212
91.110
95.26
2.49
96.02
99.83
2.29
2
184129
-
184129
96.296
101.07
3
180794
-
180794
94.552
98.82
4
186812
-
186812
97.699
102.42
5
181440
-
181440
94.890
99.42
6
185490
-
185490
97.008
101.23
坎地沙坦酯左氨氯地平片项目信息
介质体积(ml)
900
取样体积(ml)
10
补液体积(ml)
10
对照品批号
100685-201903
对照品来源
中检院
对照品使用方法
直接使用
对照品含量(%)
99.8
对照品水分(%)
0
对照品稀释倍数
4000
标示量(mg)
8
供试品稀释倍数
2
系数
1
对照品溶液
序号
称样量(mg)
A
1
A
2
A
3
A
4
A
5
A
平均
RSD%
1
15.95
171092
172931
172735
171032
172404
172039
0.53
2
16.07
170343
170462
170402
0.05
单位质量响应值
RSD%
判断
10786.14
10603.73
1.21
数据可信
供试品溶液-12407637批-pH6.8(内含0.1%Tween80)
时间
(分钟)
样品
A
1
A
2
A
平均
溶出量(%)
平均(%)
RSD%
累计溶
出量(%)
平均(%)
RSD%
5min
1
15929
-
15929
8.362
8.23
17.16
8.36
8.23
17.16
2
15988
-
15988
8.393
8.39
3
12383
-
12383
6.500
6.50
4
15669
-
15669
8.225
8.23
5
13747
-
13747
7.216
7.22
6
20303
-
20303
10.658
10.66
10min
1
46433
-
46433
24.374
24.90
13.00
24.47
24.99
13.00
2
47743
-
47743
25.062
25.16
3
37797
-
37797
19.841
19.91
4
46643
-
46643
24.485
24.58
5
48903
-
48903
25.671
25.75
6
57084
-
57084
29.965
30.08
15min
1
82300
-
82300
43.202
44.00
12.97
43.57
44.36
12.97
2
84272
-
84272
44.237
44.61
3
67114
-
67114
35.231
35.52
4
79565
-
79565
41.767
42.13
5
89888
-
89888
47.185
47.55
6
99747
-
99747
52.361
52.81
20min
1
116401
-
116401
61.103
61.83
12.82
61.95
62.68
12.81
2
117759
-
117759
61.816
62.68
3
95195
-
95195
49.971
50.66
4
109974
-
109974
57.729
58.56
5
128177
-
128177
67.285
68.17
6
139174
-
139174
73.057
74.09
30min
1
147899
-
147899
77.638
82.00
8.17
79.16
83.55
8.24
2
159046
-
159046
83.489
85.04
3
137392
-
137392
72.122
73.36
4
153738
-
153738
80.703
82.17
5
166783
-
166783
87.550
89.19
6
172450
-
172450
90.525
92.37
45min
1
175656
-
175656
92.208
92.80
3.85
94.59
95.25
3.99
2
179271
-
179271
94.106
96.58
3
163680
-
163680
85.922
87.96
4
178988
-
178988
93.957
96.32
5
182257
-
182257
95.673
98.28
6
180857
-
180857
94.938
97.79
60min
1
181399
-
181399
95.223
94.55
2.43
98.63
98.03
2.63
2
182071
-
182071
95.576
99.10
3
171686
-
171686
90.124
93.12
4
179261
-
179261
94.101
97.51
5
183241
-
183241
96.190
99.86
6
183021
-
183021
96.074
99.98
极限
1
180288
-
180288
94.640
95.21
1.42
99.11
99.74
1.51
2
182259
-
182259
95.674
100.26
3
179045
-
179045
93.987
97.98
4
180828
-
180828
94.923
99.38
5
186094
-
186094
97.687
102.43
6
179698
-
179698
94.330
99.30
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图1 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>溶剂 图2 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-1-1 图3 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-1-2 图4 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-1-3 图5 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-1-4 图6 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-1-5 图7 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-5min-片1<br>供试品溶液-1 图8 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-5min-片2<br>供试品溶液-1 图9 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-5min-片3<br>供试品溶液-1 图10 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-5min-片4<br>供试品溶液-1 图11 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-5min-片5<br>供试品溶液-1 图12 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-5min-片6<br>供试品溶液-1 图13 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-10min-片1<br>供试品溶液-1 图14 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-10min-片2<br>供试品溶液-1 图15 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-10min-片3<br>供试品溶液-1 图16 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-10min-片4<br>供试品溶液-1 图17 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-10min-片5<br>供试品溶液-1 图18 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-10min-片6<br>供试品溶液-1 图19 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-15min-片1<br>供试品溶液-1 图20 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-15min-片2<br>供试品溶液-1 图21 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-15min-片3<br>供试品溶液-1 图22 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-15min-片4<br>供试品溶液-1 图23 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-15min-片5<br>供试品溶液-1 图24 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-15min-片6<br>供试品溶液-1 图25 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-20min-片1<br>供试品溶液-1 图26 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-20min-片2<br>供试品溶液-1 图27 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-20min-片3<br>供试品溶液-1 图28 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-20min-片4<br>供试品溶液-1 图29 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-20min-片5<br>供试品溶液-1 图30 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-20min-片6<br>供试品溶液-1 图31 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-30min-片1<br>供试品溶液-1 图32 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-30min-片2<br>供试品溶液-1 图33 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-30min-片3<br>供试品溶液-1 图34 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-30min-片4<br>供试品溶液-1 图35 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-30min-片5<br>供试品溶液-1 图36 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-30min-片6<br>供试品溶液-1 图37 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-45min-片1<br>供试品溶液-1 图38 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-45min-片2<br>供试品溶液-1 图39 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-45min-片3<br>供试品溶液-1 图40 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-45min-片4<br>供试品溶液-1 图41 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-45min-片5<br>供试品溶液-1 图42 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-45min-片6<br>供试品溶液-1 图43 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-60min-片1<br>供试品溶液-1 图44 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-60min-片2<br>供试品溶液-1 图45 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-60min-片3<br>供试品溶液-1 图46 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-60min-片4<br>供试品溶液-1 图47 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-60min-片5<br>供试品溶液-1 图48 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-60min-片6<br>供试品溶液-1 图49 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-极限转速-片1<br>供试品溶液-1 图50 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-极限转速-片2<br>供试品溶液-1 图51 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-极限转速-片3<br>供试品溶液-1 图52 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-极限转速-片4<br>供试品溶液-1 图53 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-极限转速-片5<br>供试品溶液-1 图54 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-极限转速-片6<br>供试品溶液-1 图55 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-2-1 图56 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-2-2 图57 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>溶剂 图58 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-1-1 图59 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-1-2 图60 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-1-3 图61 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-1-4 图62 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-1-5 图63 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-5min-片1<br>供试品溶液-1 图64 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-5min-片2<br>供试品溶液-1 图65 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-5min-片3<br>供试品溶液-1 图66 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-5min-片4<br>供试品溶液-1 图67 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-5min-片5<br>供试品溶液-1 图68 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-5min-片6<br>供试品溶液-1 图69 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-10min-片1<br>供试品溶液-1 图70 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-10min-片2<br>供试品溶液-1 图71 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-10min-片3<br>供试品溶液-1 图72 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-10min-片4<br>供试品溶液-1 图73 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-10min-片5<br>供试品溶液-1 图74 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-10min-片6<br>供试品溶液-1 图75 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-15min-片1<br>供试品溶液-1 图76 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-15min-片2<br>供试品溶液-1 图77 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-15min-片3<br>供试品溶液-1 图78 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-15min-片4<br>供试品溶液-1 图79 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-15min-片5<br>供试品溶液-1 图80 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-15min-片6<br>供试品溶液-1 图81 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-20min-片1<br>供试品溶液-1 图82 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-20min-片2<br>供试品溶液-1 图83 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-20min-片3<br>供试品溶液-1 图84 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-20min-片4<br>供试品溶液-1 图85 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-20min-片5<br>供试品溶液-1 图86 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-20min-片6<br>供试品溶液-1 图87 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-30min-片1<br>供试品溶液-1 图88 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-30min-片2<br>供试品溶液-1 图89 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-30min-片3<br>供试品溶液-1 图90 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-30min-片4<br>供试品溶液-1 图91 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-30min-片5<br>供试品溶液-1 图92 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-30min-片6<br>供试品溶液-1 图93 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-45min-片1<br>供试品溶液-1 图94 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-45min-片2<br>供试品溶液-1 图95 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-45min-片3<br>供试品溶液-1 图96 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-45min-片4<br>供试品溶液-1 图97 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-45min-片5<br>供试品溶液-1 图98 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-45min-片6<br>供试品溶液-1 图99 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-60min-片1<br>供试品溶液-1 图100 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-60min-片2<br>供试品溶液-1 图101 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-60min-片3<br>供试品溶液-1 图102 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-60min-片4<br>供试品溶液-1 图103 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-60min-片5<br>供试品溶液-1 图104 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-60min-片6<br>供试品溶液-1 图105 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-极限转速-片1<br>供试品溶液-1 图106 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-极限转速-片2<br>供试品溶液-1 图107 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-极限转速-片3<br>供试品溶液-1 图108 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-极限转速-片4<br>供试品溶液-1 图109 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-极限转速-片5<br>供试品溶液-1 图110 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转-极限转速-片6<br>供试品溶液-1 图111 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-2-1 图112 坎地沙坦酯左氨氯地平片溶出曲线测定HPLC图谱<br>参照制剂-12407637批-pH6.8(内含0.1%Tween80)介质-桨法-50转<br>对照品溶液-2-2
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