缬沙坦氨氯地平片项目信息
介质体积(ml)900取样体积(ml)1.5补液体积(ml)1.5
对照品批号100374-202106对照品来源中检院对照品使用方法直接使用
对照品含量(%)99.9对照品水分(%)0对照品稀释倍数2000
标示量(mg)5供试品稀释倍数1系数0.7210
对照品溶液
序号称样量(mg)A1A2A3A4A5A平均RSD%
115.002570872574952578022577072581192576420.15
215.182548832577442563140.79
单位质量响应值RSD%判断
17176.1316884.981.21数据可信
长期24月-供试品溶液-2023112521批-缬沙坦-pH2.0
时间
(分钟)		样品A1A2A平均溶出量(%)平均(%)RSD%累计溶
出量(%)		平均(%)RSD%
5min1128707-12870748.99552.176.0648.9952.176.06
2149076-14907656.74856.75
3138022-13802252.54152.54
4126510-12651048.15848.16
5139677-13967753.17153.17
6140341-14034153.42353.42
10min1169336-16933664.46167.564.1364.5467.644.13
2188349-18834971.69871.79
3175754-17575466.90466.99
4169887-16988764.67164.75
5181329-18132969.02669.11
6180223-18022368.60568.69
15min1186631-18663171.04474.473.5671.2374.673.57
2205501-20550178.22878.44
3193192-19319273.54273.74
4190630-19063072.56772.75
5201296-20129676.62776.83
6196603-19660374.84075.04
20min1195217-19521774.31378.003.2874.6278.333.29
2213183-21318381.15281.50
3201751-20175176.80077.12
4202098-20209876.93277.24
5211618-21161880.55680.89
6205602-20560278.26678.59
30min1204547-20454777.86481.723.0978.3082.183.09
2222101-22210184.54785.03
3211243-21124380.41380.86
4214103-21410381.50281.94
5221719-22171984.40184.87
6214383-21438381.60982.07
45min1213162-21316281.14484.532.7981.7185.122.80
2227952-22795286.77487.39
3217261-21726182.70483.29
4221715-22171584.40084.97
5229421-22942187.33387.94
6222893-22289384.84885.44
60min1217087-21708782.63886.392.8383.3387.122.83
2234187-23418789.14789.91
3222882-22288284.84485.57
4227745-22774586.69587.41
5233144-23314488.75089.50
6226597-22659786.25886.99
90min1224139-22413985.32388.332.9186.1689.212.91
2239329-23932991.10592.02
3224593-22459385.49586.36
4232428-23242888.47889.34
5239547-23954791.18892.09
6232263-23226388.41589.29
120min1225319-22531985.77288.513.1586.7589.543.14
2240846-24084691.68292.75
3229048-22904887.19188.20
4235094-23509489.49390.50
5240404-24040491.51492.57
6224417-22441785.42886.46
时间
(分钟)		样品A1A2A平均溶出量(%)平均(%)RSD%累计溶
出量(%)		平均(%)RSD%
极限1225201-22520185.72789.232.8286.8590.402.82
2241520-24152091.93993.16
3230694-23069487.81888.97
4231667-23166788.18889.34
5242151-24215192.17993.38
6235195-23519589.53190.70
缬沙坦氨氯地平片项目信息
介质体积(ml)900取样体积(ml)1.5补液体积(ml)1.5
对照品批号100651-202307对照品来源中检院对照品使用方法直接使用
对照品含量(%)99.1对照品水分(%)0对照品稀释倍数200
标示量(mg)80供试品稀释倍数1系数1
对照品溶液
序号称样量(mg)A1A2A3A4A5A平均RSD%
116.674961277496986449803844976280498237849740370.18
216.694959467496453549620010.08
单位质量响应值RSD%判断
298382.54297303.830.26数据可信
长期24月-供试品溶液-2023112521批-氨氯地平-pH2.0
时间
(分钟)		样品A1A2A平均溶出量(%)平均(%)RSD%累计溶
出量(%)		平均(%)RSD%
5min1318074-3180745.9536.155.135.956.145.13
2346714-3467146.4896.49
3306282-3062825.7325.73
4316793-3167935.9295.93
5338405-3384056.3346.33
6344206-3442066.4426.44
10min1629834-62983411.78811.953.7611.8011.963.77
2671504-67150412.56812.58
3604531-60453111.31411.32
4624133-62413311.68111.69
5644373-64437312.06012.07
6656148-65614812.28012.29
15min1886753-88675316.59616.722.9916.6316.752.99
2927389-92738917.35717.39
3851608-85160815.93915.97
4881120-88112016.49116.52
5898741-89874116.82116.85
6914224-91422417.11017.14
20min11078219-107821920.18020.542.6720.2420.602.67
21132201-113220121.19021.25
31055697-105569719.75819.81
41086346-108634620.33220.39
51107181-110718120.72220.78
61124370-112437021.04421.10
30min11391492-139149226.04326.462.5626.1326.552.57
21457383-145738327.27627.37
31353767-135376725.33725.42
41427990-142799026.72626.82
51420140-142014026.57926.67
61431277-143127726.78826.88
45min11724466-172446632.27532.822.3232.4132.962.33
21801967-180196733.72533.87
31688009-168800931.59331.72
41771276-177127633.15133.29
51762309-176230932.98333.12
61773540-177354033.19333.33
60min11983911-198391137.13137.692.2137.3237.882.21
22068041-206804138.70538.90
31946261-194626136.42636.61
42046317-204631738.29938.49
52005240-200524037.53037.72
62032892-203289238.04738.24
90min12353203-235320344.04244.821.3744.2945.071.38
22440825-244082545.68245.94
32365417-236541744.27144.51
42416854-241685445.23445.49
52386472-238647244.66544.92
62404751-240475145.00745.27
120min12613925-261392548.92249.511.8049.2549.841.80
22705911-270591150.64350.98
32574697-257469748.18848.50
42684570-268457050.24450.57
52640867-264086749.42649.76
62652836-265283649.65049.98
时间
(分钟)		样品A1A2A平均溶出量(%)平均(%)RSD%累计溶
出量(%)		平均(%)RSD%
极限12764801-276480151.74652.551.7852.1552.961.79
22865683-286568353.63454.06
32740113-274011351.28451.68
42856547-285654753.46353.88
52796407-279640752.33752.75
62821687-282168752.81053.23
点击查看处理图标(自动生成)
　
原始图谱(等待粘贴贴图标)